What is inside Laminine?
OPT9 contains a natural combination of nutrients, including amino acids, glycopeptides, and oligopeptides that come from fertilized eggs, isolated natural plant proteins (yellow pea), and natural marine elements (purified shark cartilage) that work together to form a super food or nutraceutical for the support of both the mind and the body.
The Health Effects
Laminine has been associated with a variety of potential health benefits, including: increased strength and vitality, improved stamina and energy, increased libido (in both men and women), reduced stress, improved sleep, quicker recovery after workout and improved muscle tone, increased lean muscle mass, increased alertness and mental clarity, reduced “brain fog”, improved mood, improved calmness and happiness (Laminine has been called “the happy pill”), and overall improved sense of well being.
These various effects may all be related to the significant reduction of the stress hormone cortisol (by about 50 percent) after the ingestion of Laminine, as well as increases in the happy chemical, serotonin. Additionally, Laminine provides the precursors (building blocks) to nutritionally support the production, and maintenance of laminin in the body. Laminin is the protein network foundation for most cells and organs in our bodies.
Laminins are an important and biologically active part of the basal lamina, and influence how the cells of our body differentiate (stem cells), migrate, hold together (adhesion) and survive. Laminin has been called the ”rebar of the human body” much like rebar (strong metal rods) structurally hold together and strengthen concrete used to build buildings and highways.
What exactly is PESE, and how much is known about its benefits?
Proto Embryonic Stage Extract (PESE) is the name the manufacturer has given the ingredient in Laminine that is derived from the liquid whites of partially incubated (9 days old) fertilized organic hen eggs. The cholesterol‐containing yolk is excluded. PESE contains the most potent and balanced combination of amino acids, as well as other factors such as Fibroblast Growth Factor (FGF). Amino acids derived from such fluids combined with the growth factors are able to enhance brain function because they are precisely engineered to support the
most complex stage of development of a living creature, the beginning of life. This beginning is the most critical stage in our development, just like the take‐off is the most complex function in flying an airplane, or the foundation (and structural rebar) is in construction, and is the most essential function in the life of a building.
The health benefits of the hen egg have been known for centuries. Recently, further investigation of the mechanism of the development of an embryo in an egg during incubation has revealed the scientific equivalent of the “miracle of life”. The potency of the nutrients available to the embryo at the latter stage of development stage has always been assumed to be high, but it was only recently that the chemical structure of the original egg solids for these critical stages was obtained. During this stage, oligopeptides with small molecular weights were identified. These short chains of amino acids are able to cross the digestive barrier without breaking down or changing the ratios and proportions. Peptides are far more potent than other neurotransmitters, requiring only small amounts to produce a profound effect. Heat can destroy these critical protein factors, and Laminine should not be heated over 118 degrees. It should be protected from prolonged exposure to heat, and should never be mixed into steaming hot liquids, or baked into foods.Additionally, the uptake of the Fibroblast Growth Factor (FGF) (present in PESE) by the embryo sharply increases and the FGF present have been isolated through a patented process precisely at the right stage of incubation, extracted and freeze dried to bring the “miracle of life” benefits to humans.
Extracting PESE before the peptides and FGF are “used up” to build organs and bones, allows us to provide this building, repairing, maintenance mechanism of perfectly balanced amino acids, peptides and growth factors to humans. While virtually unknown in the United States until very recently, PESE has been marketed successfully as a nutritional supplement in Scandinavia for many years.
How is Fibroblast Growth Factor (FGF) helpful to humans?
The precise blend of oligopeptides may be seen as building blocks, but without a bridge, or a master builder/director. The role of such a director is fulfilled by a growth factor known as the Fibroblast Growth Factor, or FGF. FGF is prolific in PESE, as well as in the human placenta. A detailed day‐by‐day study was performed in 1988. Discovered four decades ago in the seventies, and also existing as a peptide, this FGF is critical in the development of embryos, including humans. However, it is not found to be circulating in the human adult bodies. FGF is responsible for building the linings in the blood vessels, creating the infrastructure for the nutrients to flow to critical areas of the brain and organs. Research credits FGF with the potential to directly affect many neurologic disorders because of the ability of FGF to affect the growth of neurites.
Neurites are signal senders (Axons) and signal receivers (Dendrites) that are attached to the brain neurons.
Research has also clearly demonstrated that new cell cultures show a dramatic increase in peptide and amino acid uptake in the presence of FGF. This result supports the hypothesis that embryonic growth is influenced by a very precise mechanism, which combines unique combinations of amino acids, peptides and FGF.
Since FGF is not circulating in adults, multiple research projects on the effects of FGF serums to cure neurologic disorders have been carried out. Fundamental to the research is the fact discovered by Altman in 1962 that neural STEM cells are formed by the body in response to abnormalities, and are resident in certain zones of the brain undergoing biologic stress. The brain is therefore ready to repair the damage, and these cells have shown to differentiate into a wide range of neurons. Neurons derived from such neural stem cells are capable of migrating to various regions of the Central Nervous System.
Use of vegetable proteins
Vegetable protein has an essential amino acid profile, which is very close to that of the ideal protein for human nutrition (FAO/WHO 1985 and 2002). For Laminine, a patented process further isolates these proteins in order to eliminate unnecessary compounds which can neutralize the benefits of the essential amino acids.
The result is an compound which is high in Glutamic acid, (further enhancing the cognitive function of the brain), branched chain amino acids (to counter insomnia), Lysine (to control release of serotonin, controlling moods), and Arginine (promoting Nitric Oxide and growth hormone formation). These specially isolated proteins create a synergistically potent composition to enhance brain activity.
Use of Marine Proteins
The high levels of Glycine in the specially extracted marine protein (purified shark cartilage) used in Laminine, combined with a significant amount of hydroxyproline to stabilize the glycine, makes it a primary candidate for a terrific brain food. By itself, Glycine is a neurotransmitter, primarily utilized by the brain to control glutamate levels. In combination within OPT9, it becomes a powerful force to enhance memory function in the brain.